C. LaShan Simpson

C. LaShan Simpson

Assistant Professor

Biomedical Engineering
Agricultural and Biological Engineering

Office: 208 Agricultural and Biological Engineering
clsimpson@abe.msstate.edu
P 662.325.8279
Cellular Engineering Laboratory

Education

Ph.D., Bioengineering, Clemson University.
M.S., Bioengineering, Clemson University.
B.S., Bioengineering, Clemson University.

Experience Record

  • Jan. 2013 - Present, Assistant Professor in Biomedical Engineering, Mississippi State University, Mississippi State, MS
  • May 2010 – Dec. 2012, Post-Doctoral Research Assistant, Rice University, Houston, TX
  • Aug. 2003 – May 2010, Graduate Research Assistant, Clemson University, Clemson, SC

Specialty Areas

Tissue Engineering, Cardiovascular Disease, Osteogenesis, Biomineralization, Animal Models, Cell Culture, Histology, Cell and Gene Therapy

Research Interests

  • Examine the relationship between vascular calcification and bone mineralization
  • Develop polymeric delivery vehicles for cell and gene therapy of cardiovascular disease

Publications

Journal Publications

  • Sonnet, C, Simpson, CL, Olabisi, RM, Sullivan, K, Hipp, J, Lazard, Z, Gugala, Z, Gannon, F, Stice, S, Peroni, J, Weh, M, Sevick, E, Heggeness, M, Davis, AR, West, JL, Olmsted-Davis, EA. Cell Based Gene Therapy for Fracture Healing in a Rat Femoral Critical Size Defect. Journal of Orthopedic Research. Accepted
  • Simpson, CL, Lindley S, Eisenburg C, Basalyga D, Starcher B, Simionescu D, Vyavahare N., Towards Cell Therapy for Vascular Calcification: Osteoclast-Mediated Demineralization of Calcified Elastin. Journal of Cardiovascular Pathology, Cardiovascular Pathology, 16 (2007) 29-37.

Proceedings and Published Abstracts

  • Simpson, CL, Lazard, Z, Olabisi, RM, Davis, AR, Olmsted-Davis, EA, West, JL. Spinal Fusion through a Non-Invasive Injectable Cell-Based Gene Therapy Method. BioMedical Engineering Society. Atlanta, GA. Oct, 2012. Oral Presentation.
  • Lu, Y, Simpson, CL, Lazard, Z, Olmsted-Davis, EA, Davis, AR, West, JL, Tan, I, Darne, C, Hall, MA, Robinson, H, Sevick, E. Multimodal Tomography for Localization of BMP2 Transduced Cells for Spine Fusion. World Molecular Imaging Conference. Dublin, Ireland. Sept, 2012. Poster Presentation.
  • Simpson, CL, Lazard, Z, Olabisi, RM, Davis, AR, Olmsted-Davis, EA, West, JL. A Non-Invasive Injectable Cell-Based Gene Therapy for Spine Fusion. Southern BioMedical Engineering Society. Houston, TX. May, 2012. Oral Presentation.
  • Simpson, CL, Lazard, Z, Olabisi, RM, Davis, AR, Olmsted-Davis, EA, West, JL. A Non-Invasive Injectable Cell-Based Gene Therapy for Spine Fusion. TERMIS-NA. Houston, TX. Dec, 2011. Oral Presentation.
  • Simpson, CL, Sonnet, C, Olabisi, RM, Sullivan, K, Davis, AR, Davis, EM, West, JL. Critical Size Defect Repair through a Gene Therapy Approach. BioMedical Engineering Society. Hartford, CT. Oct, 2011. Oral Presentation.
  • Sonnet, C, Simpson, CL, Olabisi, RM, Sullivan, K, Hipp, J, Lazard, Z, Gugala, Z, Gannon, F, Stice, S, Peroni, J, Weh, M, Sevick, E, Heggeness, M, Davis, AR, West, JL, Olmsted-Davis, E. Cell Based Gene Therapy for Fracture Healing in a Rat Femoral Critical Size Defect. American Society for Bone and Mineral Research. San Diego, CA. Sept, 2011.
  • Olabisi, RM, Simpson, CL, Sonnet, C, Lazard, Z, Sullivan, K, Davis, AR, Davis, EA, West, JL. Robust Femoral Critical Size Defect Repair via Injection of Hydrogel Microencapsulated Transduced Allogeneic Cells. Gordon Research Conference: Biomaterials & Tissue Engineering, Holderness, NH, 31 July, 2011.
  • Simpson, CL, Sonnet, C, Sullivan, K, Olabisi, RM, Davis, AR, Olmsted-Davis, EA, West, JL. Critical Size Defect Repair Through a Gene Therapy Approach. Gordon Research Conference: Tissue Repair and Regeneration. New London, NH. June, 2011.
  • Simpson, CL, Sonnet, C, Sullivan, K, Olabisi, RM, Davis, AR, Olmsted-Davis, EA, West, JL. Critical Size Defect Repair Through a Gene Therapy Approach. Society for Biomaterials: Biomaterials Day. College Station, TX. May, 2011.
  • Olabisi, RM, Sonnet, C, Simpson, CL, Lazard, Z, Sullivan, K, Davis, AR, West, JL, Olmsted-Davis, EA. Hydrogel Microencapsulation Permits Critical Size Defect Repair via Gene Therapy. Society for Biomaterials Annual Meeting. Orlando, FL. April, 2011.
  • Olabisi, RM, Sonnet, C, Lazard, Z, Simpson, CL, Davis, AR, Olmsted-Davis, EA, West, JL. Critical Size Defect Repair through a Single Injection. Orthopedic Research Society Annual Meeting. Los Angeles, CA. January, 2011.
  • Rajgariah, A, Olabasi, RM, Simpson, CL, West, JL. Determining the Number of Cells Microencapsulated within PEGDA Hydrogel Microspheres. Biomedical Engineering Society Annual Meeting. Austin, TX. October, 2010
  • Simpson, CL, Cheluvaraju, C, Vyavahare, N. Site-Specific Osteoclast-Mediated Cell Therapy for Vascular Calcification. Society for Biomaterials Annual Meeting. Seattle, WA. April 2010
  • Chelevaraju, C, Simpson, CL, Vyavahare, N. Cathepsins are Upregulated in Vascular Calcification. Society for Biomaterials Annual Meeting. Seattle, WA. April 2010
  • Simpson, CL, Vyavahare, N. Cell Therapy as a Novel Treatment for Vascular Calcification. South Carolina Science, Technology and Health Conference and South Carolina Academy of Science Annual Meeting. Columbia, SC. April 2009
  • Simpson, CL, Yuan Y, Simionescu D, Bateman T, Vyavahare N. Osteoclast Precursors from Bone Marrow Resorb Elastin Calcification. Biomedical Engineering Society Annual Meeting, Chicago, IL. October 2006
  • Weinbrenner, DR, Burdick, JA, Simpson, CL, Lickfield, G, Laberge, M. Dextran Hydrogel Used as a Phospholipid Delivery System for Viscosupplementation, Society for Biomaterials Annual Meeting, Pittsburgh, PA. April 2006
  • Simpson, CL, Lindley S, Basalyga D, Simionescu D, Vyavahare N. Osteoclast-Mediated Demineralization of Calcified Elastin. Society for Biomaterials Annual Meeting, Memphis, TN. April 2005
  • Simpson, CL, Lindley S, Simionescu D, Vyavahare N. International Society for Applied Cardiovascular Biology Biennial Meeting, Savannah, GA. March 200

Awards and Honors

  • Women In Science and Engineering Award for Years of Service, 2007, Clemson University, Clemson, SC
  • Austin T. Moore Award for Outstanding Graduate Student in Bioengineering, 2006, Clemson University, Clemson, SC
  • Diversity Fellowship, 2005 - 2010, Clemson University, Clemson, SC
  • South Eastern Alliance for Graduate Education Professoriate, 2005 - 2010, Clemson University, Clemson, SC