




CARDIOVASCULAR TISSUE BIOMECHANICS LABORATORY
Our research interest is focused on cardiovascular tissue biomechanics, with emphasis on the structure-function relationship of heart valves, myocardium, and blood vessels. The goal is to: (i) (i)identify the essential mechanisms that determine the optimal physiological functions, (ii) (ii)determine the structural and mechanical abnormality in diseased tissues, and (iii) (iiifacilitate better surgical intervention and biomimetic replacement development.
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Dr. Jun Liao Assistant Professor of Biomedical Engineering EDUCATION Postdoctoral, Bioengineering, University of Pittsburgh, PA Ph.D., Applied Biomedical Engineering, Cleveland Clinic Foundation/Cleveland State University, OH M.S., Material Science and Engineering, Sichuan University, China B.S., Physics, Sichuan University, Chengdu, China ¡¡ ------------------------------------------------------------------------------------------------------------- RESEARCH Research Interests Soft Tissue Biomechanics and Simulation
Cardiovascular Tissue Engineering (heart valve, cardiac tissue, etc.) Non-invasive Characterization of Cardiovascular Tissues Research Funding 2005-2007: ¡°Effects of Decellularization and Recellularization on Porcine Aortic Valve Biomechanics¡± American Heart Association Beginning Grant-in-Aid (Role: PI, Co-I: Dr. Michael S. Sacks) 2007-2008: Schillig Special Teaching Grants, Mississippi State University (Co-I: Dr. James Warnock) 2007-2008: "Noninvasive Characterization of Myocardial Infarction by Magnetic Resonance Imaging" MAFES Special Funding (Role: PI, Co-PI: Dr. Song Zhang, Dr. Ron McLaughlin, and Dr. Shane Burgess) 2008-2009: ¡°Development of a Novel Recellularization Approach for Tissue Engineering Heart Valve¡± Research Initiate Program, MSU (Role : PI) Current Research Biomechanics of Engineered Cardiac Tissue Development of a Novel Recellularization Approach for Tissue Engineering Heart Valve Noninvasive Characterization of Myocardial Infarction by Magnetic Resonance Imaging Multi-scale Human Body Simulation Effects of Decellularization and Recellularization on Biomechanics of Porcine Aortic Valve Previous Projects Collagen Fibril Kinematics under Biaxial Loading by Synchrotron Small Angle X-ray Scattering Cellular Deformations in Micro-integrated Elastomeric Electrospun Scaffolds under Biaxial Stretch Micromechanical Properties and 3D Structure of Collagenous Tissues and Valve Interstitial Cells Investigation of the Mechanical and Structural Properties of Mitral Valve Chordae Tendineae ¡¡ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- RECENT PUBLICATIONS (Selected from 23 peer-reviewed publications. Other 9 publications are in material science field)
------------------------------------------------------------------------------------------------------------- MEMBERSHIPS AND REVIEWER FOR PROFESSIONAL JOURNALS Biomedical Engineering Society (BMES) American Heart Association (AHA) American Society of Mechanical Engineering (ASME) Society For Biomaterials (SFB) IEEE Engineering in Medicine and Biology Society, IEEE Society Reviewer of Journal of Biomechanics Reviewer of Journal of Biomechanical Engineering Reviewer of Osteoarthritis and Cartilage Reviewer of Acta Biomaterialia Reviewer of Polymer International Reviewer of Annals of Biomedical Engineering Reviewer, Region II Bioengineering Peer Review Committee, American Heart Association ¡¡ ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CONTACT INFORMATION
Mississippi State University
Tel: 662-325-5987 Fax: 662-325-3853 Email: jliao@abe.msstate.edu |
LABORATORY MEMBERS
Benjamin Weed, Ph.D. student ¡¡ Bo Wang, Ph.D. student ¡¡ ¡¡ Lauren Beatty, Master student ¡¡ Ali Borazjani, Undergraduate student ¡¡ Mina Tahai, Undergraduate student ¡¡ Anna Hood, Undergraduate student ¡¡ ¡¡ Joe Chen, Undergraduate student ¡¡ ¡¡ ALUMNI ¡¡ Hugh Jones - The Institute of Orthopedic Research and Education in Houston
Willie Brown - undergraduate student, LSAMP Scholarship |